Computational Neuroscience

Hubel & Wiesel (1965)

They discovered orientation-tuned cells which response to bar of light at specified angles.

on-center, off-surround receptive fields

These cells respond when center of cell is stimulated

off-center, on-surround receptive fileds

These cells repond which sorrounding area is activated

Examples

• Oriented RF: V1

• Center-surround RF: LGN and retian

• Retina –> LGN –> V1
• number of LGN cells converge to a single v1 cell

Pre-synaptice neuron

• a neuron that fires the neruotransmitter as a result of action potential

Post-synaptic neuron

• a neuron that receives the neurotransmitter and may experience and action potential

• A transmitter can influence the function of a neuron.

  • It can influence trans-membrance ion flow either to increase (excitatory) or to decrease (inhibitatory) the probability that a cell which it comes in contact will produce an action potential